May 28, 2025

Are EMFs Harmful or Healing? Understanding Natural, Manmade & Therapeutic EMFs

EMFs Friend or Foe? EMFs are a hot topic of discussion these days, especially on social media. Many people are (rightfully) concerned about excessive EMF exposure, but most are confused about exactly what EMFs are, the differences between man-made and natural (sometimes called native) EMFs, how they affect our biology, and how EMFs (good and bad) are produced by the myriad devices we use each day. In this article, we will dig into all of this and more, with the goal of educating and empowering consumers to make safe, healthy choices about EMF exposure. What are EMFs? EMFs are produced by the movement of electrically charged particles and consist of two inseparable components: electric and magnetic fields. When these fields oscillate, they travel through space as electromagnetic radiation. While some EMFs remain close to their source (like static electric or magnetic fields), others radiate outward and can interact with biological systems. Understanding how they behave - and how the body responds - is key to using them wisely.     EMFs vary in characteristics, including: Frequency – how often the field oscillates per second (measured in Hz). Wavelength – the distance between wave peaks. Intensity – the strength of the electric or magnetic component. Waveform – the shape of the wave (sine, square, etc.). Coherence – how synchronized or orderly the waveforms are. Pulsing – whether the field is continuous or switches on and off rhythmically. Biological impact depends not only on these factors, but also on how close the field is to the body and whether exposure is short-term or continuous. These details matter more than whether an EMF is “natural” or “manmade.”   Natural vs. Manmade EMFs Natural EMFs are those the body evolved with over millennia. Sunlight, for instance, provides visible light as well as invisible ultraviolet (UV) and infrared (IR) rays. The Earth itself generates a powerful, steady magnetic field and a weak but essential electric field. Natural resonances like the Schumann frequencies pulse in extremely low frequencies (ELF), helping regulate brainwaves and circadian rhythms. These EMFs tend to be low in intensity, rhythmically patterned, and biologically coherent. They fluctuate in ways the body recognizes, often in harmony with other cycles, such as sunrise and sunset, weather systems, and seasons. They support functions like sleep, hormone balance, mitochondrial activity, and mood.   Manmade EMFs have become a dominant presence in our environment over the last century. These include: Power lines and household wiring – Power lines emit ELF electromagnetic fields that oscillate in sync with the electrical grid. Power line fields are continuous and pervasive, especially in urban and suburban areas, while devices like power cords, and chargers emit ELF fields if they are powered. TV and radio broadcasts - Traditional broadcast systems use a wide range of radio frequencies to transmit audio and video signals. Though distant from the body and less intense individually, they contribute to the overall EMF environment. Cell Towers, Smartphones, Wi-Fi, and Bluetooth - Cell towers and phones emit pulsed, modulated microwave signals for voice and data. Bluetooth is considered a low-power technology, but because devices like earbuds and wearables are in constant skin contact, biological exposure may be more significant than power levels suggest. Wi-Fi routers emit pulsed high frequency radiation to transmit date wirelessly throughout home and buildings. These EMF sources expose users to high frequency radiation almost continuously. Smart Meters - Smart meters emit sharp bursts of high frequency radiation, often hundreds of times a day, to transmit utility data wirelessly. Their signals fall in the sam range as Wi-Fi but are uniquely problematic due to proximity to living spaces and frequent pulsing. Appliances and electronics - Appliances and electronics often produce stray electric and magnetic fields, especially when plugged in. These EMFs differ not just in source, but in structure. They are often pulsed, modulated to carry date, emitted 24/7, and delivered at much higher intensities or in close contact with the body (such as ear buds or cell phones). They are biologically novel, meaning the body hasn’t had evolutionary time to adapt to them. EMFs emitted by these sources contribute to what is often called “electrosmog”, which can be described as an invisible haze of artificial electromagnetic radiation that now fills our homes, workplaces, and public spaces. As more wireless and electronic technologies are layered into daily life, the electrosmog EMF load continues to grow, creating a baseline level of exposure that is unprecedented in human history. To put this into context, it is estimated that exposure to EMFs around the 1Gz frequency band has increased by more than a quintillion times in just over a century. Therapeutic manmade EMFs, on the other hand, are intentionally designed to support health and healing. The two most used therapies are: Photobiomodulation Photobiomodulation is the use of specific wavelengths of non-ionizing light to influence biological function, particularly at the cellular level. The use of red and near-infrared light is commonly referred to as Red Light Therapy and is typically delivered through panels or flexible wraps. Research suggests that the most effective light intensities fall within a range that is comparable to safe levels of natural sunlight. By mimicking the wavelengths and gentle intensity of natural sunlight, these devices help recreate the EMFs of natural light in a targeted, therapeutic way. Pulsed Electromagnetic Field Therapy Pulsed Electromagnetic Field (PEMF) Therapy uses pulsing magnetic fields to stimulate biological processes in the body. While the Earth’s magnetic field is static and steady, PEMF therapy introduces rhythmic pulses to mimic natural patterns (such as biological electric rhythms), making the field dynamic and biologically engaging. By pulsing at frequencies that align with Earth-based rhythms, such as the Schumann Resonance (~7.83 Hz), PEMF therapy delivers magnetic fields designed to support cellular repair, circulation, and nervous system balance.   Not All EMFs Are Harmful It’s easy to label all EMFs as dangerous, especially in a culture increasingly aware of electrosmog. But not all EMFs are harmful, and some are profoundly beneficial.  Here’s what research has shown across the spectrum for the different types of EMFs present in our environment: Natural EMFs: Sunlight and Circadian Rhythms -Sunlight acts as the body’s primary circadian pacemaker, helping synchronize the sleep-wake cycle, hormone secretion, and metabolic processes through direct input to the brain’s suprachiasmatic nucleus. UVB and Vitamin D Production - Ultraviolet B (UVB) radiation stimulates the production of vitamin D in the skin, which supports immune function, bone metabolism, and has been linked to improved mood and reduced risk of depression. Sunlight and Serotonin - Sunlight exposure may boost mood through mechanisms beyond vitamin D—specifically by increasing serotonin levels in the brain, a neurotransmitter associated with calmness, focus, and emotional stability. Schumann Resonances and Brain Activity -Schumann resonances—natural electromagnetic standing waves centered around 7.83 Hz—closely align with alpha brainwave activity and may play a role in regulating mental states, emotional balance, and sleep cycles. Earth’s Magnetic Field and Biological Regulation - The Earth’s static magnetic field, though constant and low in intensity, has been linked to biological processes such as orientation, circadian timing, and melatonin regulation. Some studies suggest it acts as a stabilizing background influence on the nervous system. Ionizing Radiation from Natural Sources - Not all natural EMFs are inherently beneficial. Overexposure to ultraviolet radiation from the sun can cause DNA damage, accelerate skin aging, and increase the risk of skin cancer. Other forms of natural ionizing radiation (like cosmic gamma rays and solar X-rays) can also damage cells and contribute to background radiation exposure.   Therapeutic Manmade EMFs: Photobiomodulation – Photobiomodulation (especially red/near infrared light therapy) has been shown to reduce pain and inflammation, support healthy circulation, and speed up healing in both skin and deeper tissues. It works by improving energy production inside cells and modulating oxidative stress, making it useful for everything from muscle recovery to wound care. Studies also suggest benefits for mood, brain function, athletic performance, and skin rejuvenation. PEMF (Pulsed Electromagnetic Field Therapy) - PEMF therapy has been shown to reduce inflammation, increase blood flow, promote tissue regeneration, and even support healing of bone and tendon. It has been found to be helpful in supporting athletic performance, speeding recovery from exercise, and preventing injuries.   Non-Therapeutic Manmade EMFs: Oxidative Stress - Exposure to non-ionizing EMFs, such as those from Wi-Fi and mobile devices, has been associated with increased oxidative stress. This oxidative stress can lead to cellular damage and has been implicated in various health concerns. Disruption of Calcium Signaling - EMFs can activate voltage-gated calcium channels, leading to elevated intracellular calcium levels. This disruption in calcium signaling can affect numerous cellular processes and has been linked to potential health risks. DNA Damage - Research indicates that exposure to non-ionizing EMFs can cause genetic damage, such as DNA strand breaks and chromatin conformation changes. Such genetic alterations may increase the risk of mutations and have been observed in various cell types. Circadian Rhythm Disruption – Although research has been mixed, EMF exposure may affect melatonin production and disrupt circadian rhythms. This interference with the body's natural sleep-wake cycle can have broader implications for overall health. Reduced Fertility - Studies have found that non-ionizing EMFs can negatively impact female reproductive health (including effects on oocytes, ovarian follicles, hormonal balance) and sperm count. These changes may lead to decreased fertility and other reproductive issues.   ______________________________________________________________________________________________ Many natural EMFs, like sunlight, are essential for human health. Therapeutic EMFs harness these beneficial frequencies and structure them in a way the body can use. On the other hand, non-therapeutic manmade EMFs - those not designed with biology in mind - have been linked to biological harm. _____________________________________________________________________________________ Manmade EMFs Done Right Not all EMF-based therapies are created equal. While devices used for Red Light Therapy and PEMF devices can offer profound health benefits, they can also unintentionally introduce harmful EMFs into the body—especially when the devices are poorly designed. High levels of magnetic field emissions, flicker, stray current, and wireless communication features like Bluetooth can all contribute to a hidden "EMF load" that undermines the very benefits these therapies are meant to deliver.   Therapy that heals, not harms At fringe, we believe that therapeutic EMF devices should support the body, not stress it. That’s why our Red Light Therapy products are engineered with EMF-conscious design principles that prioritize user safety. By minimizing unnecessary electromagnetic exposure and mimicking natural EMF patterns in both wavelength and delivery, our devices provide powerful therapeutic benefits without adding to the invisible burden of electrosmog.       Here's how we do it No Bluetooth or wireless connectivity – this eliminates constant RF emissions. External power supply on our panels – keeps electric & magnetic fields away from the body. Flicker-free light output – supports nervous system regulation & avoids sub-perceptual stress. Biomimetic wavelengths and irradiance – replicates natural red & near-infrared light from sunlight. Battery-powered wraps – eliminate wall current entirely for a low-EMF experience during use.   Safe & biologically aligned  Meanwhile, many "smart" therapeutic devices on the market prioritize app control and convenience over biological safety. These features often involve permanent Bluetooth or Wi-Fi connectivity, keeping RF radiation active near the body, even when the device is not in use. What’s marketed as “smart” is often out of sync with the body’s natural biology and may ultimately do more harm than good.  When it comes to manmade therapeutic EMFs, smart design means staying close to nature and using modern engineering to deliver powerful, biologically aligned therapies without introducing avoidable stressors.   At Fringe, that’s our commitment: Therapy that heals, not harms. Conclusion EMFs aren’t inherently friend or foe. They’re simply the products of nature and technology. Some are natural (like the rhythms of sunlight or the Earth’s magnetic field) while others  (like the constant digital noise from wireless networks and power grids) can disrupt biological balance. The question isn’t whether EMFs are good or bad, it’s whether they’re in harmony with the systems our bodies are built to understand. At Fringe, our devices are built to emit EMFs that heal, not harm. We design every product with intention to reduce invisible stress, align with nature, and deliver therapeutic energy in its most biologically compatible form. Our Red Light Therapy products are designed with smart, low-EMF engineering: no Bluetooth, no flicker, external power supplies, and biologically aligned wavelengths and intensity. We believe therapeutic EMFs should support healing without adding to the body’s invisible electrosmog burden, and we build every product with that principle in mind.

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May 15, 2025

Light & Vibration Therapy – An Aid for Incontinence?

Urinary incontinence is one of the most common pelvic health issues affecting women in the US, with a recent survey finding that more than 60% report having the condition, and more than 30% report having symptoms at least every month. Despite the widespread prevalence, it remains a topic that most are reluctant to talk about. Whether it’s the occasional leak while laughing or a more persistent urgency that disrupts daily life, incontinence can erode confidence, limit activity, and affect intimate relationships. Despite how common it is, many women are left to navigate urinary incontinence alone, unsure where to go for support or what options are    At Fringe, we believe that women deserve real, research-backed tools to care for their pelvic health from the comfort and privacy of their homes. The Fringe Pelvic Wand was designed with this in mind, and is a therapeutic device that combines red, near infrared, and blue light therapy with customizable vibration therapy to support pelvic tissue, muscle tone, circulation, and microbial balance. In this article, we’ll explore the science behind light and vibration therapy for urinary incontinence and describe how the Fringe Pelvic Wand can be a practical, empowering part of your daily pelvic health routine.   Understanding Urinary Incontinence Urinary incontinence isn’t a single condition but rather a symptom with many potential causes. The two most common types include: Stress Urinary Incontinence: Leakage caused by pressure on the bladder during movement, coughing, or laughing. This is often due to weakened pelvic floor muscles or connective tissue. Urge Urinary Incontinence: A sudden, intense urge to urinate, sometimes followed by involuntary leakage. This is typically related to nerve dysfunction or overactive bladder signals. Factors like pregnancy, childbirth, menopause, hysterectomy, obesity, and aging all increase the risk of developing urinary incontinence. Conventional treatments range from pelvic floor exercises to medications, physical therapy, and in some cases, surgery. But many women are seeking non-invasive, natural tools to improve symptoms, especially those that can be used at home. That’s where light and vibration therapy come in. How Light Therapy Supports Pelvic Health Light therapy, also known as photobiomodulation, involves applying specific wavelengths of light to tissue to stimulate healing, reduce inflammation, increase circulation, and modulate biological processes. The Fringe Pelvic Wand includes three therapeutic wavelengths: Red light (630 nm): Promotes collagen and elastin synthesis, reduces inflammation, supports tissue healing, through mechanisms including mitochondrial energy production and improving circulation Near-infrared light (830 nm): Has affects similar to red light but penetrates more deeply. Blue light (415 nm): Offers antimicrobial effects, especially for yeast and bacterial infections So how does this relate to urinary incontinence? Improving Tissue Strength & Elasticity Red and near-infrared light have been shown to increase the synthesis of collagen and elastin. These proteins are integral to maintaining the strength of the vaginal wall and pelvic floor connective tissues, areas that are often weakened in women, especially those with stress urinary incontinence. Increasing Blood Flow These wavelengths also increase nitric oxide production, causing vasodilation and enhanced blood flow. Better circulation results in improved oxygen and nutrient delivery to tissues, supporting healing and muscle function, which are both critical for proper bladder functioning. Blood flow may also increase through the synthesis of new blood vessels, a process called angiogenesis. Modulating Nerves & Pain Pathways In some types of incontinence, nerve signaling may be disrupted and pain pathways activated. Red and near-infrared light may modulate nerve activity and reduce local inflammation, which may help to reduce overactive pain or urgency signals from the bladder and pelvic floor. Supporting the Microbiome An often-overlooked component of pelvic health is the vaginal microbiome. Dysbiosis, or microbial imbalance, can increase susceptibility to infections, inflammation, and irritation. Blue light has been shown to reduce pathogens like Candida, while red light may support beneficial bacteria like Lactobacillus which is important for microbiome health. Disruptions in the microbiome are a risk factor for urinary tract infections, which are a risk factor for incontinence. The Role of Vibration Therapy Vibration therapy offers a second therapeutic modality, especially valuable for activating and strengthening pelvic floor muscles, increasing circulation, and even reducing pain. The Fringe Pelvic Wand provides four levels of mechanical vibration, from gentle (10 Hz) to strength-building (120 Hz). Research shows: Low-frequency vibration (10 or 50 Hz): Helps relax tight pelvic floor muscles, improve proprioception, and increase blood flow High-frequency vibration (90 or 120 Hz): Stimulates reflexive contractions via the pudendal nerve, strengthening pelvic floor muscles in women who struggle with voluntary control How may vibration therapy help with urinary incontinence? Improving Tissue Strength & Integrity Vibration therapy, especially low intensity vibration, may have many effects on cells associated with the structural integrity of the female pelvis, including collagen and muscle. Stronger pelvic floor muscles are associated with reduced urinary incontinence.   Increasing Blood Flow Vibration therapy may also increase blood flow, which may help to deliver oxygen and nutrients to the tissues of the pelvis and improve functioning of the bladder and pelvic floor muscles. Modulating Pain Signals Pain signals from the pelvis/bladder may be modulated by vibration therapy, including neuropathic pain, low back pain, and muscle pain. Urinary incontinence is associated with pain in conditions including interstitial cystitis/bladder pain syndrome, vulvodynia, pelvic floor myofascial pain syndrome, and neurogenic bladder disorders like Multiple Sclerosis. Regulating Muscle Tone Balanced pelvic floor muscles with proper tone are essential for proper urinary continence. Vibration therapy may help both to decrease spasticity in muscles that are overactive, as well as improve voluntary muscle contraction, such as those of the pelvic floor, which are poorly controlled in between 30 and 50% of women. The Fringe Pelvic Wand: Dual Therapy for Urinary Incontinence The Fringe Pelvic Wand brings together red, near infrared, and blue light therapy with a range of customizable vibration modes from low to high in one comfortable, easy-to-use device. It was designed to meet a broad spectrum of pelvic health needs:  + Light Therapy Specs Wavelengths: 630 nm (red), 830 nm (near infrared), 415 nm (blue) Intensity: 20–40 mW/cm² (adjustable to 50%) Built-in Timer: 10-minute automatic shut-off Modes: Mode 1: Red + Near Infrared Light (deep tissue healing) Mode 2: Blue light only (antimicrobial support) Mode 3: Red only (gentle tissue support for heat/light-sensitive users) + Vibration Therapy Specs Low amplitude, rapid acceleration Built-in Timer: 10-minute automatic shut-off Modes: Mode 1: 10Hz Mode 2: 50Hz Mode 3: 90Hz Mode 4: 120Hz This level of control allows you to personalize therapy sessions to your unique needs, including calming inflammation, strengthening muscles, balancing microbes, or all of the above.       How to Use the Fringe Wand for Urinary Incontinence Here's a suggested routine to start with   Pelvic Light & Vibration Therapy Safety  Light and vibration therapies are well-established as safe, but here are a few precautions: Avoid use if you have known light sensitivity, or are on medications that increase sensitivity to light Don’t use on open wounds Only use water-based lubricants (oil-based can damage the silicone wand material) Check with your provider before use if you're pregnant   A New Era of At-Home Pelvic Health Urinary incontinence is a highly prevalent condition that impacts millions of women, yet effective, accessible, and non-invasive treatment options remain limited. The growing body of scientific research surrounding light therapy and vibration therapy offers compelling evidence that these modalities may play a valuable role in supporting pelvic tissue health, improving muscle tone, modulating nerve activity, and restoring microbial balance, all of which are relevant to the underlying causes of incontinence. The Fringe Pelvic Wand was designed with these mechanisms in mind. It provides a multi-modal therapeutic approach that is grounded in emerging science, integrating red, near infrared, and blue light with adjustable vibration frequencies to support the complex structures and functions of the female pelvic floor. Whether used on its own or as a complement to pelvic floor physical therapy, the Fringe Pelvic Wand offers a novel, at-home tool for women seeking to improve urinary continence, restore comfort, and support long-term pelvic health. As with any health intervention, individual responses may vary, and we encourage women to consult with their healthcare providers when integrating new therapies into their wellness routines.

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April 1, 2025

Deconstructing Red Light Therapy Intensity: Why MORE Isn’t Always BETTER!

Red Light Therapy Intensity: Why Higher Power Isn’t Always Better for Results “High intensity, medical grade Red Light Therapy”. This is a statement that is often made about Red Light Therapy devices, implying that to see real therapeutic benefits, that a device must be really powerful. But is this actually true? What does the scientific evidence say about high intensity Red Light Therapy devices?  Let’s dig into the research. But first, we need to define what light “intensity” is. Light intensity (also known as power density) describes the amount of light being delivered by a device. Also sometimes called irradiance, it’s usually measured in units called mW/cm2. Intensity is related to power, which is the rate at which energy is delivered, measured in Watts (W). If we look at that energy per square cm of exposure site, we get W/cm2, or mW/cm2 – our intensity. So, intensity is the amount of energy from a device at any given moment, and if we consider that as a function of time of exposure, we get the energy density (measured in J/cm2), which is the total energy delivered over time. This combination of intensity with exposure time is also referred to as the “dose” of light delivered by the treatment.   Let’s dig into the assumption that higher powered devices are required to derive benefit by exploring five lines of evidence.   1. Where did the idea that high intensity Red Light Therapy is required for therapeutic benefit come from? This idea comes from the fact that for decades, virtually all research and applications of photobiomodulation were done with lasers, which are high intensity devices. Research into Red Light Therapy began in the 1960’s, and lasers dominated the field until around the early 2000’s, when LED’s (light emitting diodes) began to be studied. The scientific literature is comprised of around 85% studies using lasers as light sources, with the rest using LED’s. Companies making higher powered devices are often trying to get close to the power of lasers, citing laser research that shows benefits. However, hundreds of studies have now shown that LED Red Light Therapy yields many benefits, such as reducing pain and inflammation. And, LED’s have four important advantages over lasers: (1) they’re safer, (2) they’re cheaper, (3) they can be easily used at home, and (4) LED’s can cover a greater area of the body allowing more tissue to receive light. Given this, an important question for researchers in the field to address was whether the benefits of Red Light Therapy were specific to something about laser light, or whether those benefits could be replicated using LED’s. In 2018, an analysis that reviewed the comparative evidence of lasers versus LED’s concluded that “most of these comparisons provisionally suggest that lasers could indeed be replaced with LED’s without significant worsening of the results.” This is despite major differences in power outputs, which demonstrates that high intensity lasers are not required for therapeutic benefits. 2. Does the research on Red Light Therapy demonstrate that a certain intensity range is needed to observe therapeutic benefits? There is an excellent comprehensive database online of published photobiomodulation research studies that describes the details of thousands of Red Light Therapy studies. We can look at this database to compare the intensity (power) of studies relative to their results, and to see if there are clear trends, such as a requirement for high intensity/power to yield benefits. Most studies using LED’s have an intensity between 10 and 100mW/cm2 and are most commonly between 10 and 50mW/cm2. For lasers, the intensity is much higher, based on the different characteristics of the light produced. Positive results spanning a wide range of outcomes are observed, and there are no clear trends related to light intensity. Some studies use extremely low intensity LED lights, some use higher intensity LED lights, and some use high intensity lasers. Although studies of certain light intensities are sometimes used to support specific products, when you look at the totality of the research, the main conclusion that can be drawn is that exposure to red and/or near infrared light across a wide range of light characteristics, including intensity, yields biological benefits.   3. Can devices with different intensities be used to deliver the same “dose” of light? Theoretically, the time variable can be manipulated when using devices with different intensities to deliver the same “dose” of light. Mathematical calculations show that higher intensity devices used for shorter periods of time can deliver a comparable dose of light to lower intensity devices used for longer periods of time. However, some research has demonstrated that our bodies don’t seem to absorb photons the same way when they are delivered at a high intensity, suggesting that “dose” may not simply be a mathematical calculation of intensity and time. For example, a recent comprehensive review of studies of red light therapy for the brain found that “NIR light with low-power density (15–30 mW/cm2) is a more effective intervention than that with high-power density (40–90 mW/cm2)." 4. If low, moderate, and high intensity devices have been shown to deliver therapeutic benefits, are there reasons for preferring low or moderate intensity rather than high? Yes, there are reasons to prefer low to moderate intensity devices as compared to high. For example, high intensity light can increase oxidative stress, which is harmful to biological health. When wounds are treated with low/moderate intensity red light therapy, markers of oxidative stress initially increase and then decrease dramatically as healing progresses. However, when wounds are treated with high intensity red light therapy, oxidative stress remains high. Similarly, levels of antioxidant enzyme activity (which reduces oxidative stress) increase with low/moderate intensity red light therapy but not with high intensity light. This suggests that low/moderate intensity Red Light Therapy reduces oxidative stress, while high intensity Red Light Therapy may cause it to increase. High intensity light also carries a risk of heating tissues and causing thermal damage.    5. Are there biological reasons to expect that there could be an upper limit to Red Light Therapy intensity when it comes to therapeutic benefits? Yes! Researchers have carefully studied the biological effects of Red Light Therapy and have clearly concluded that “dose” matters. If the dose is too low, there is no benefit; similarly, if it is too high, there is also no benefit – and there is the potential for harm. This is called a biphasic dose response, also known as the Arndt Shulz law. Picture this as an inverted U curve. If the dose is too low or too high, there will be minimal response, but there is a relatively wide range of doses in the middle range that are beneficial. As described by Dr. Michael Hamblin, “It has been consistently found that when the dose of is increased a maximum response is reached at some value, and if the dose in increased beyond that maximal value, the response diminishes, disappears and it is even possible that negative or inhibitory effects are produced at very high fluences.” Because “dose” is a function of intensity and time, using high intensity devices for too long can easily yield a dose of light that will not be beneficial, and may even be harmful.  These five lines of evidence clearly illustrate that the assumption that high intensity devices are needed to achieve benefit is not accurate. It is the dose that creates the benefit – and dose is a function of intensity and time. While it may be appealing to use a higher intensity light to get the treatment done faster, this carries risks including thermal damage due to heating tissues, as well as a risk of causing oxidative stress.  The tendency when using a high intensity device – which would require a treatment time of only a few minutes (or even less) – is to overdo it. For at-home devices, low to moderate intensities leave more wiggle room in terms of both safety and benefits.  Fringe Red Light Therapy Intensity Fringe Red Light Therapy products were designed to deliver light at an intensity of 20-40mW/cm2, which is the approximate intensity of the sun. This has been described as the “sweet spot” between higher intensities, which can have harmful effects, and lower intensities, which will have no effect at all. Although there are no clear distinctions between low, moderate, and high intensity devices, the intensity of Fringe Red Light Therapy devices would most appropriately be termed as low/moderate and stands in contrast to many devices on the market, which are 100mW/cm2 or even higher. At this intensity, our products can safely be used for treatment periods between 10 and 30 minutes, and our products are programmed with built-in timers to deliver a safe and effective dose of light.  We verify the intensity of our products using third party testing, which is important because independent research has found that many commercial home-based Red Light Therapy products do not deliver light as advertised.  Take Home Points The idea that high intensity Red Light Therapy devices are needed for therapeutic benefits originated from decades of research using high intensity lasers; however, subsequent research has demonstrated that lower intensity LED powered devices can yield comparable results.   An analysis of the totality of published Red Light Therapy research (using both lasers and LED’s) shows that benefits can be seen when using devices that span a very wide range of intensity, from low to high. This is consistent with research that shows the effective “dose” of Red Light Therapy follows a U-shaped curve, with benefits spanning a wide range but which has a lower and upper limit. The “dose” of light is determined by its intensity and the treatment time, although research has shown that delivering light quickly using a high intensity device may not be as effective as delivering it more slowly using a lower intensity device, suggesting that the “dose” is not the only factor that determines benefits. High intensity light can increase oxidative stress and the risk of thermal damage, so care must be taken when using high powered devices to limit treatment times, which can be difficult to do when using at-home devices. The Verdict? Research evidence does not support the claim that high intensity Red Light Therapy devices are required for therapeutic benefits. Using low to moderate intensity devices yields results that are comparable to using high intensity devices, with some research even demonstrating greater efficacy. Low to moderate intensity devices also have the advantage of greater safety and can be safely used at home as part of a regular wellness regime. Choose a device that suits your needs and preferred treatment conditions, and which delivers both red and near infrared light at an appropriate intensity. Combine red light therapy with an anti-inflammatory diet and supplements, regular exercise, stress management, and good sleep hygiene for best results.

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March 12, 2025

Red Light Therapy & Traumatic Brain Injury

    What is Traumatic Brain Injury? Traumatic Brain Injury (TBI) occurs when the brain is damaged by an external force, like an impact, blast, or rapid acceleration/deceleration. Common causes of TBI include falls, sports injuries, vehicle accidents, and physical assaults. Damage from TBI’s can lead to long-lasting and even permanent impairment of brain function. TBI’s are common injuries in the US, with approximately 1.5 million Americans experiencing a TBI annually.    TBI is considered an umbrella term that refers to any brain injury caused by an external source. TBI’s can be categorized by severity, ranging from mild to severe, and have unique characteristics: Mild TBI – Causes temporary confusion and headache. Moderate TBI – Causes prolonged confusion and cognitive impairment. Severe TBI – Causes significant cognitive deficits and long-term complications. TBI’s can also be categorized by timeframe, including both acute (short-term) and chronic (long-term) effects. The acute phase last from hours to weeks, while the chronic phase lasts from weeks to years, depending on the severity of the TBI.    Two TBI-related terms that may be familiar to people are concussions and Chronic  Traumatic Encephalopathy (CTE). Concussions are a type of mild TBI, and although symptoms usually resolve within days to weeks, they can still have long-term effects, especially with multiple incidents. One potential long-term consequence of repeated concussions is CTE, a progressive neurodegenerative disease believed to be caused by repeated head injuries, including multiple mild TBIs.  Treatment for TBI varies greatly depending on the severity of the injury. In general, it involves stabilization, symptom management, and rehabilitation. The primary goal of treatment during the acute phase is to protect brain tissue and focuses on cognitive rest and addressing symptoms. In the chronic phase, the primary goal of treatment is to restore cognitive, motor, and emotional function.  Emerging treatments such as Red Light Therapy may be beneficial in supporting the brain during both the acute and Shop Red Light Therapy Head Wrap   How does TBI affect the Brain Before we consider how Red Light Therapy may be used to support brain health following TBI, let’s take a closer look at the three major pathological processes that occur in the brain during this type of injury.    Neuroinflammation: TBI causes neuroinflammation, which occurs in the hours to days following the injury. Neuroinflammation is inflammation of the brain, which can be helpful in the short term but is harmful when prolonged, leading to chronic neurodegeneration. Excess neuroinflammation is linked to brain fog, mood disorders, and an increased risk of neurodegenerative diseases such as CTE. Oxidative stress: Following a TBI, the brain produces excessive amount of reactive oxygen species (ROS), which can lead to oxidative stress. Oxidative stress can overwhelm our antioxidant defenses and cause damage to cells in the brain, worsening brain injury.  Impaired brain energy metabolism: TBI impairs brain energy metabolism, particularly the ability of the brain to use glucose, which leads to a metabolic crisis where neurons are deprived of energy. After an initial phase of excessive glucose use, there is a decrease in glucose availability that can last from days to weeks, which makes neurons more vulnerable to damage and impairs healing. These three factors interact and include many overlapping molecules. For example, both neuroinflammation and impaired brain energy metabolism can lead to an increase in ROS production, further worsening oxidative stress. Similarly, impaired energy metabolism exacerbates neuroinflammation. This creates a self-perpetuating cycle of damage, which is why TBI recovery can be slow and why some people experience persistent symptoms for weeks, months, or even years following the injury. How does Red Light Therapy support brain function? Red Light Therapy is a promising tool for supporting the brain during TBI because it targets all three foundational brain pathologies, including neuroinflammation, oxidative stress, and impaired brain energy metabolism. Using both red and near infrared light (especially near infrared, which has deeper penetration), Red Light Therapy delivers wavelengths that interact with light sensitive molecules inside brain cells.      Here's how Red Light Therapy affects neuroinflammation, oxidative stress, and brain energy metabolism:  Neuroinflammation: Red and near infrared light wavelengths have anti-inflammatory effects, and unlike anti-inflammatory medications (such as NSAID’s), do not cause side effects. Studies have found that light therapy affects levels of many molecules involved in inflammation, including ROS, reactive nitrogen species, and prostaglandins. Red and near infrared light therapy have specifically shown to reduce neuroinflammation.  Oxidative stress:  Light is absorbed in cells by molecules called chromophores, many of which are found inside the mitochondria. Mitochondria are involved in regulating the production the ROS that cause oxidative stress when present in high amounts. Light therapy has been shown to modulate oxidative stress and ROS production. Impaired brain energy metabolism: Through its impact on mitochondria, light also affects metabolism. In addition to regulating ROS production, mitochondria also make ATP, which is the energy currency of the cell, via a chain of molecules that includes cytochrome c oxidase. Cytochrome c oxidase is activated by both red and near infrared light, which increases ATP synthesis and provides more energy to brain cells. As well, there are additional effects of Red Light Therapy in the brain that may help to support healing from TBI. This includes increasing brain blood flow, supporting brain adaptability, and regulating neuron cell death. Collectively, there are many ways in which Red Light Therapy may be used therapeutically in TBI, and these have been explored in several clinical and pre-clinical studies of both acute and chronic TBI.   Is there evidence to support the use of Red Light Therapy in TBI? Yes! Red Light Therapy has been investigated in several studies of TBI using a range of different experimental approaches. These studies can be broken down by timeframe into both acute and chronic TBI, as well as by study type, including clinical (using humans as subjects) and pre-clinical (using animals as subjects).   Acute TBI The acute phase of TBI immediately follows the onset of injury. Unfortunately, this creates some challenge in coordinating and executing research studies, since it is difficult to recruit human subjects into a research study who have just experienced a head injury. As a result, most of the research in this TBI phase has been done using animals given a head injury in a controlled environment. In a 2023 systematic review of 17 animal studies that used Red Light Therapy immediately post-TBI, it was found that early light therapy intervention could improve neurological outcomes and reduce the size of trauma-associated brain lesions. Optimal results were associated with both red and near infrared light, initiation within 4 hours post-injury, and up to three daily treatments. One human study was included in the review of Red Light Therapy for acute TBI, which suggested safety and feasibility, but treatment efficacy could not be determined.     Chronic TBI Many more human studies have explored the use of Red Light Therapy in the chronic phase of TBI, which occurs weeks to months after the initial trauma. In a 2024 review of 16 human studies, overall improvements in neuropsychological outcomes and increased cerebral blood flow following transcranial PBM were observed. Here are some highlights of the clinical research findings:         How can I use Red Light Therapy in TBI? 2019 study of 12 military veterans with chronic TBI lasting more than 18 months – Following six weeks of application of both red and near infrared light to the head using LED lights, neuropsychological scores and brain blood flow were improved.  2020 case report of 23-year professional hockey player with a history of concussions, and symptoms of headaches, mild anxiety, and difficulty concentrating - Following 8 weeks of application of near infrared light to the head using LED lights, many positive findings were observed, including increased brain volume, improved brain connectivity, increased brain blood flow, and improved neuropsychological test scores. 2023 study of four retired professional football players with suspected CTE – Following application of near infrared light to the head using LED lights three times per week for six weeks, a wide range of improvements were noted, including improved sleep, reduced depression, decreased PTSD, and decreased pain. Analysis of brain function showed several improvements.    Collectively, research looking at the use of Red Light Therapy to support healing from TBI has yielded positive outcomes, both subjective (such as improved mood and decreased pain), and objective (such as increased brain volume and blood flow). There is stronger support for the use of Red Light Therapy in chronic TBI, but pre-clinical evidence supports the potential for benefit during the acute phase of injury.    TBI Recovery Managing TBI involves a combination of stabilization, symptom relief, and rehabilitation, each playing a crucial role in recovery. Red Light Therapy is a safe and effective tool that can support healing throughout all three stages. While it can be conveniently done at home using a Red Light Therapy device, professional supervision is recommended during the acute phase to ensure safe and effective application.   When exploring the range of available options, here are four things to consider: Light wavelength – The wavelength of light determines its color, with red light in the range of 620-700nm and near infrared light in the range of 700-1100nm. Although near infrared has been used most often to support healing from TBI, some studies have also found benefit from red light. Light with wavelengths between 600 and 1300nm have been found to penetrate maximally into the brain. So, look for products that provide both RL and NIRL in combination. Light intensity - Light intensity refers to the amount of light being delivered by a device, also referred to as power density. Studies of Red Light Therapy and TBI have used a range of intensities, from 10-100mW/cm2, and there is no clear indication that a particular intensity must be used. Devices across a range of intensities may provide benefit, and consumers aren’t limited to a specific intensity range. Type of device - Your personal level of comfort with a device is important. If it isn’t easy to use, and if it doesn’t feel good on your body, you probably won’t use it consistently. Many consumers find the most convenient devices to use are wireless, with a rechargeable battery. It is also important to use a device that can be adjusted to fit snugly on the head. Think about your personal preferences and choose a device that fits your criteria. Light Source - Light therapy is administered using either laser or LED lights. While early light therapy research was done using lasers, LED lights have become much more popular over the last decade. For at home use, look for a device that uses LED lights as safe and affordable option.   The next step after selecting a Red Light Therapy device is to determine the treatment protocol. During the acute phase of TBI, it is recommended to consult with your health care provider to get their professional guidance regarding the most appropriate protocol for your case. During the chronic phase of TBI, support from a health care professional is also recommended, but people may be more independent during this period. Based on available clinical research, 10-40 minute treatment sessions, 3 to 5 times a week, are recommended. Do not exceed more than one session every 24 hours.   Conclusion Red Light Therapy is a safe, affordable, and highly effective tool for supporting at-home recovery from TBI. By targeting the three core drivers of brain injury—oxidative stress, impaired metabolism, and neuroinflammation—it offers a scientifically backed approach to healing. Research suggests benefits across all stages of TBI, from the critical early hours to years post-injury. When choosing a device, look for red and near-infrared LED technology that aligns with your needs for comfort and convenience, empowering you to take an active role in your recovery.   Shop Red Light Therapy Head Wrap   For more information about Fringe light products, go to: https://fringeheals.com/shop-all-products/

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February 3, 2025

Incandescent vs LED Lights in Red Light Therapy

    Red Light Therapy has been investigated in thousands of research studies over the last 50 years. Until the early 2000’s, most studies used lasers as the light source, but more recently, LED lights have become popular due to their affordability, safety, and ease of at-home use. LED lights are now widely used in Red Light Therapy devices, including the devices we make at Fringe. Other light sources, such as incandescent lights, are also sometimes promoted for use in Red Light Therapy, but it’s important to recognize that incandescent lights are not equivalent to LED’s when it comes to reaping the well-recognized benefits of this powerful healing modality.   In this article, we’ll explore the characteristics of LED and incandescent lights, how the two light types can (and cannot) be used in Red Light Therapy, and what to look for in a Red Light Therapy device.  Comparison of LED and Incandescent Lights LED lights have many important characteristics that are superior to incandescent lights, including: Characteristics LED  Incandescent Energy Efficiency 80-90% more efficient than incandescent, as most energy is converted to light Very inefficient – 90 to 95% of energy is lost as heat, and only 5 to 10% is converted to light Lifespan 25,000 to 50,000 hours (10 to 25x longer than incandescent) 1,000 to 2,000 hours (needs frequent replacement Heat Output Minimal heat emission, stays cool to the touch High heat emission, can become too hot to touch Long-Term Cost Lower long-term cost due to energy savings and longer lifespan Higher long-term cost due to frequent replacements and high energy use Durability Shock-resistant, does not break easily Fragile, glass can break easily Environmental Impact Eco-friendly, no toxic materials, low energy consumption Higher energy use, shorter lifespan, increases waste There are also some areas where LED’s can be inferior to incandescent lights, including: Characteristics LED  Incandescent Flicker Potential Some LEDs flicker which can cause eye strain No flicker; provides continuous, steady light EMF Emission May emit higher EMF’s due to electronic drivers Minimal EMF emission, since it does not use electronic drivers Blue Light Exposure Can be quite high Low, more natural warm light   However, NONE of these characteristics are necessarily an issue with Red Light Therapy devices. Why we don’t NECESSARILY need to be concerned about these limitations (Flicker, EMF, Blue Light Exposure) with Red Light Therapy devices: Many Red Light Therapy devices do not flicker – a reputable company will demonstrate this using third party testing (we do!) EMF emission – it’s absolutely true that a LOT of Red Light Therapy devices emit way too many EMF’s, but they don’t have to. At Fringe, we’ve designed our panels so that the electronic driver is 3 feet away from the panel, so there is almost no EMF emission from the panel itself. Our wraps are battery powered; batteries create energy through chemical reactions, which generate negligeable EMF’s.  Blue Light Exposure – Red Light Therapy devices contain red and near infrared LED’s, which don’t emit blue light (of course, blue light LED’s are also an option…!) What about Blue Light Therapy using LED’s? Isn’t blue light from LED lights harmful? This is true but isn’t the whole story.  Blue light from devices like ipads, phones, etc. is found in a very narrow spectrum of wavelengths. This is “foreign” to our body, as it is different than the blue light that comes from the sun. In contrast, blue light used in Blue Light Therapy emits a wider spectrum of wavelengths that closely mimics the distribution of blue light in sunlight. This light spectrum has been found to be antimicrobial, which is why it is used for applications like acne.  No matter what, though, it’s still important to avoid getting blue light in the eyes. Is light from an incandescent light the same as from an LED? Incandescent lights produce light in a “full spectrum”, including red and near (and also far) infrared light. This is what makes the light from incandescents “warm” in terms of color, and also generates a lot of heat, making them hot to the touch. It’s also why these lights are used for things like heating terrariums. In order to make an incandescent light exclusively red, a red film or coating is placed on the glass that filters out other colors allowing only the red (and sometimes infrared) wavelengths to pass through. The filament inside still produces other colors, but they’re mostly blocked by the coating.  LED lights used in Red Light Therapy will produce light in the red (if using red diodes) or near infrared (if using near infrared diodes) spectrums. Many devices include both types of diode, and the type of light is produced by using a semiconductor material that naturally produces red or near infrared light. Red Light Therapy doesn’t use white LED lights like you would find in a house lamp.  Red and near infrared light are the same in terms of wavelength no matter what the source. The difference is that incandescent lights produce full spectrum light and then block the other light from being emitted, while LED lights (red or near infrared) emit ONLY the light in that color spectrum. If the red and near infrared light is the same, can incandescent lights be used instead of LED’s in Red Light Therapy? Incandescent lights CAN be used to activate the eye to brain pathway that is responsible for some of the benefits of Red Light Therapy. In this pathway, photoreceptors in the retina are activated and influence the function of the suprachiasmatic nucleus in the brain. This helps regulate the circadian cycle and also has an influence on mood and stress hormones. These lights are great for lighting up a room. Incandescent lights CANNOT be used as easily as LED’s to activate the light to tissue pathway that is responsible for the majority of benefits of Red Light Therapy. In this pathway, light enters through the skin (or other tissue) and activates photoreceptors in cells, such as cytochrome c oxidase in mitochondria. To achieve this benefit, the skin/tissue has to be close (6 inches or less) away from the light source. Because incandescent lights get hot and are fragile, they aren’t a substitute for durable LED’s that don’t generate much heat. Incandescent bulbs also generate scattered light, which doesn’t allow for good skin/tissue penetration. There is limited research showing that under some circumstances, incandescent lights may activate this pathway, but their functional limitations do not make them a substitute for LED’s.  Most of the benefits of Red Light Therapy (reduced inflammation, faster tissue healing, reduced oxidative stress) comes from the light to tissue pathway. Incandescent lights do not work to activate this pathway effectively. It’s also important to note that almost none of the benefits of Red Light Therapy that have been observed in thousands of research studies over the last 50 years used incandescent light, with most studies using laser or LED light.  How do I know if my Red Light Therapy device is safe to use? Here are some things to look for: Use of red and near infrared light in evidence-based spectrums. Fringe Red Light Therapy devices use red light at 660nm and near infrared light at 850nm, which have been demonstrated in many research studies to be beneficial. No flicker Low to no EMF’s. Low irradiance (this is also called power or intensity. And yup, you want this low. A lot of companies are selling products that are quite high intensity, and this can potentially be harmful). Irradiance in the range of 20-40mW/cm2 mimics the sun, and has been shown in multiple research studies to be both safe and effective.  A good company will prove these by sharing analyses done by third party testing.  Why choose Fringe Red Light Therapy devices? We use evidence-backed wavelengths of red and near infrared light. Our devices are no flicker and generate low to no EMF’s.  We use a safe and effective sun-like intensity of light, at between 20 and 40mW/cm2. All of our products are tested by an independent third party lab, and we share this analysis with our consumers. Our products are created by a team of medical professionals who carefully review and use published scientific evidence to inform how we manufacture.   Take home message: Incandescent lights are a great option for lighting up a room, creating a warm and ambient red light that may have benefits related to activation of the eye to brain pathway which helps to regulate the circadian rhythm and mood. Incandescent lights cannot be used as a substitute for LED lights to activate the tissue to cell pathway that is responsible for benefits including reduced inflammation, decreased oxidative stress, and improved tissue healing.  Of the thousands of research studies on Red Light Therapy, only a small number used incandescent lights, so their clinical efficacy has not been clearly demonstrated. High-quality Red Light Therapy devices will use both red and near infrared LED lights and will be no flicker, generate low to no EMFS, and deliver light at a sun-like intensity that is both safe and effective for everyone, including kids and pets. 

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December 20, 2024

Light Therapy & Menopause

Menopause Menopause is the natural transition that occurs when a woman stops menstruating, which usually happens between the ages of 40 and 58. The term “transition” refers to a change from one state to another, which is a very apt descriptor for what happens during menopause. Hormonally speaking, menopause marks a shift to an entirely new hormonal milieu, which not surprisingly, can be quite challenging.  Hormonal Changes During Menopause The hormonal changes that accompany menopause are dramatic. From perimenopause (the stage leading up to menopause) to post-menopause (the stage following menopause), levels of estrogen and progesterone drop to a fraction of their previous levels. This sharp decline is not linear, instead showing fluctuations that can create a whirlwind of physical and psychological symptoms. Levels of testosterone also decrease during this transition.   The effects of menopause The effects of menopause on the brain and body are similarly dramatic. Although these vary widely between individuals, there are many common symptoms, including hot flashes, loss of libido, vaginal dryness, sleep issues, weight gain, dry skin, hair thinning, digestive changes, sexual dysfunction, urinary symptoms (including incontinence) and mood disturbances. Some menopausal symptoms are local, occurring mainly in the pelvic region, while others (such as hot flashes) are felt throughout the body. Similarly, some symptoms are transient while others cause persistent and long-term physical changes.  The experience of menopausal symptoms is extremely common. Overall, it is estimated that 75-80% of women suffer from symptoms related to menopause, of which 20-30% are considered severe. Approximately 75% of women worldwide experience hot flashes, while 40-60% suffer from sleep issues. As many as 83% of women report experiencing vaginal dryness, often with associated pain during intercourse. Research has found that 9 in 10 women weren’t educated about menopause, and since talking about these symptoms has long been viewed as “taboo”, women often suffer menopause symptoms in silence, leaving them unable to access tools that might help to alleviate them.  Improving access to supportive tools during menopause is a critical public health issue. This includes natural and alternative therapies, as well as novel tools such as light therapy. Light - including red, near infrared, and blue light – may help to alleviate several of the challenging symptoms of menopause, including sleep and mood issues, vaginal dryness and atrophy, hair loss, overactive bladder, sexual dysfunction, cognitive and digestive changes, and skin problems. Read on to learn how light therapy can be used to support women’s health during this important transitional period. Light therapy Before we can explore how light therapy can be used to support women’s health during menopause, we first need to answer the question: what is light therapy? The answer is really quite simple. Light therapy (also known as photobiomodulation) is the application of light with specific wavelengths to the body for the purposes of influencing biology. In theory, light therapy can use any wavelength of light, but the most commonly used are red, near infrared, and blue. The use of red and near infrared light is commonly referred to as “red light therapy”. All three wavelengths of light may be useful in supporting women during menopause, although red and near infrared light have the greatest utility.   Research has shown that light therapy has many effects on a cellular level. Briefly, with red and/or near infrared light, the most notable observed effects include an increased production of cellular energy, reduced inflammation, decreased oxidative stress, decreased pain, increased blood flow, enhanced collagen and supportive tissue production, and improved microbiome health (gut and vagina). Blue light is mainly used to destroy pathogenic microorganisms like yeast and bacteria.  Light Therapy & Menopause Given that there is such a wide range of menopausal symptoms (note that for simplicity, symptoms related to peri-, meno- and post-menopause are being considered here as “menopausal” symptoms), it is likely that the various physiological effects of light therapy will be more or less relevant for certain ones.  For example, some of the changes seen during menopause – such as vaginal atrophy, dryness, and urinary incontinence - are due in part to a decrease in blood flow and loss of connective tissue in the pelvis. While specific research into using light therapy to treat these symptoms is still sparce, researchers have proposed that based on existing scientific evidence, red light therapy may alleviate these symptoms by stimulating the production of collagen and elastin, supporting bladder function, and enhancing blood flow.    Many symptoms of menopause are also experienced in other states, and we can look to those conditions for clues regarding how to use light therapy to alleviate the same symptoms during menopause. This includes anxiety and depression, hair loss, sleep disturbances, acne, digestive issues, and infections. While research specific to these symptoms in menopausal women is lacking, there is clear evidence that light therapy (with red, near infrared, and/or blue light) can be helpful in other conditions, and we can extrapolate from there to the menopausal state. Based on the known physiological effects of light therapy, and the evidence of benefits in a range of clinical conditions, we propose that the use of red, near infrared, and/or blue light may help to alleviate several of the most common symptoms experienced by women during this life transition, including: Mood: Mood changes are a common experience during menopause, with many women reporting increases in anxiety and depression. Light therapy (with red and near infrared light) has been shown to reduce depressive symptoms in both humans and animals, likely due to improvements in mitochondrial function, increased brain blood flow, and decreased neuroinflammation. A 2009 clinical trial found a reduction in symptoms of depression and anxiety in as little as a single session. The effects of light therapy on mental health are so compelling that a recent systematic review concluded that it is “strongly recommended” as a treatment for moderate depressive disorder and is “recommended” for the treatment of anxiety disorder. Studies of red light therapy and depression often apply light therapy directly to the skull, while some use an intranasal approach. Cognition: Cognitive changes, such as memory loss, are also commonly experienced by women during menopause. Researchers have shown in a series of controlled clinical studies that near infrared light therapy improves cognition in young and middle-aged healthy adults when applied to the prefrontal cortex of the brain. Cognitive improvements were accompanied by changes in brain function, including increased brain blood flow. In 2019, a meta-analysis of all the research looking at the effects of light therapy (including near infrared light, or near infrared and red light in combination) found that the overall effect on cognition was positive, leading the authors to conclude that light therapy is a “cognitive-enhancing intervention in healthy individuals”.                                    Hair Loss: Menopausal women frequently report hair loss and thinning. The ability of light therapy to induce hair growth was observed in studies conducted more than 50 years ago. Early clinical trials used primarily red light, and the effectiveness of these studies led to the development of several red light therapy devices for hair loss. Subsequent studies have shown that near infrared light also stimulates hair growth, with red and near infrared light improving hair growth in androgenetic alopecia, which is the most common type of hair loss that affects both men and women. Light impacts hair growth through effects on mitochondria, which lead to increases in the length of time the hair follicle spends in the growth phase.                                                                                             Overactive Bladder: Overactive bladder, involving a frequent urge to urinate, is a urinary symptom experienced during menopause. Overactive bladder often results in urinary incontinence. Although research related to light therapy and overactive bladder is limited, one study found that application of red light to the abdomen three times per day for 12 weeks resulted in a reduction of urinary incontinence as compared to a control group, suggesting a potential benefit in this condition.    Skin Changes: During menopause, many women report skin changes, including acne, dryness, altered pigmentation and wrinkles. Light therapy has been widely used in spas and dermatology clinics for its effects on skin health, in addition to at-home use. Red and near infrared light is helpful in the treatment of wrinkles,  psoriasis, acne, hyperpigmentation, and rosacea, while blue light is helpful in the treatment of acne. Studies show results such as smoother skin; wrinkle reduction and improved skin elasticity; and normalization of skin pigmentation. The effect of red light therapy on wrinkles can be quite dramatic, with one study showing a 30% decrease in eye wrinkle volume. Gut: Gut dysbiosis, involving changes in the gut microbiome, are common around the time of menopause. Estrogen is known to affect the gut microbiome and similarly, some of the microbes in the gut microbiome (called the estrobalome) are able to influence levels of estrogen in the body. Keeping the microbiome healthy during menopause is essential, and light therapy (with red and near infrared light) may provide some support. Animal research has shown that when red or near infrared light was applied to the abdomen of mice, the composition of the microbiome shifted to include more of a bacterial strain that is associated with better health. In humans, red and near infrared light applied to the abdomen of Parkinson’s disease patients modulated the composition of the gut microbiome, with a shift towards more “healthy” bacteria, and in a case report of a patient with breast cancer, application of near infrared light to the abdomen was associated with increased diversity of gut microbes, which is considered to be a healthy change Vaginal Dysbiosis: Similar to the gut, the vagina has a microbiome, and menopause can cause dysbiosis in this region as well. Hormone-induced dysbiosis can increase the vaginal pH and change the composition of the microbes, which is associated with bladder dysfunction and bladder pain syndrome. Light therapy, particularly with red and near infrared light, is proposed as being a positive modulator of the vaginal microbiome. There are several proposed mechanisms, including modulation of nitric oxide. Nitric oxide is important for the lactobacillus species that dominate in the vagina that are known to decrease during menopause.                                                                                                                                    Sleep: As already mentioned, sleep disturbances are experienced by 40-60% of menopausal women. Light is a primary regulator of the body’s circadian rhythm, so it is not surprising that light therapy has effects on sleep. Application of red and near infrared light during wakefulness improves sleep quality in people with cognitive decline, Guillain-Barré Syndrome, fibromyalgia and stroke. When red light therapy is applied during sleep, there is an increased clearance of waste products from the brain and improved flow of cerebrospinal fluid, which are required for optimal brain health. Blue light triggers wakefulness, suppressing melatonin, so direct exposure of the eyes to blue light should be limited to daytime hours. Vaginal Infections: Vaginal infections with yeast and bacteria are more common during menopause due to the changes in estrogen, vaginal pH, and vaginal dryness that occur. In addition to their positive effects on the microbes in the gut and vagina, red and near infrared light have also been shown to have effects on pathogenic (harmful) microorganisms in the female pelvis. Red light has been shown to be helpful in treating vaginal candida, as has blue light. Specifically, blue light at 415nm (the same wavelength as in the Fringe Pelvic Wand) had the most potent anti-candida effects. Blue light has also been shown to be helpful in the treatment of vulvovaginitis. Vaginal Atrophy: Vaginal Atrophy, Dryness & Sexual Dysfunction: The loss of estrogen during menopause causes many changes to the integrity of tissues in the vagina. This results in tissue atrophy and dryness, which can cause great discomfort, especially during sex. The main structural connective tissues are collagen and elastin, which provide strength and flexibility to the vagina. These changes occur for a variety of reasons, including a decrease in blood flow which results from the loss of estrogen. Application of red and near infrared light is known to increase blood flow by increasing levels of nitric oxide. It has also been shown to increase the synthesis of collagen and other supportive connective tissue including elastin. Suggesting that red and near infrared light may help with tissue support and rejuvenation during menopause.  Light Therapy Products for Menopause While early research on light therapy used primarily lasers, more recent research has found that LED’s can also be used, which also have the advantage of applying light to a larger area of the body as well as an improved safety profile. The use of LED in red/near infrared/blue light therapy devices has also greatly reduced the cost of treatment, making it something that can be done in the comfort of one’s own home. A wide range of products are available, each of which is uniquely suited to address specific needs. The four most useful light therapy products to address the symptoms of menopause are: Red light therapy panel Panels usually deliver red and near infrared light, ideally with the option to use separately or in combination. Panels can be used to treat most body parts, including the face, chest and back. They’re great for supporting sleep and mood, when light should be entering through the eyes. They can also support digestion when directed towards the skin of the abdomen, as well as the skin on the face. The Fringe Red Light Therapy Panel delivers both wavelengths of light at the same “sweet spot” intensity as the sun. shop our panel Red light therapy wraps Red Light Therapy Wraps deliver light directly to the skin and can be applied to specific body parts, such as the head and abdomen. They should also deliver both red and near infrared light. Wraps have the advantage of being cordless and very convenient to use. The Fringe Red Light Therapy Head Wrap delivers light to the head (including red and two wavelengths of near infrared light) and is ideally suited to support mood, cognition, and hair loss. The Fringe Red Light Therapy Wrap has a rectangular shape and can be applied to the abdomen to support bladder function and digestion. shop our wraps           Light therapy face mask Like wraps, face masks deliver light directly to the skin but are specifically contoured to the face. Due to the antimicrobial effects of blue light, it should be included in face masks for the treatment of acne along with red and near infrared light. The Fringe Red Light Therapy Face Mask delivers all three wavelengths of light to support skin health, including acne, wrinkles, pigmentation, and more. shop the mask               Light therapy pelvic wand Light therapy pelvic wands are inserted directly into the vagina, delivering light directly to the vaginal tissues that are affected by menopausal hormonal changes. The Fringe Light Therapy Wand delivers red, near infrared, and/or blue light to support blood flow and tissue rejuvenation, which may help alleviate vaginal dryness, atrophy, and sexual dysfunction. shop the wand       To recap Menopause is a time of dramatic hormonal changes, which create uncomfortable symptoms for many women. Light therapy is a safe and effective tool that may be used to alleviate a wide range of menopausal symptoms in the comfort of one’s own home. Red and near infrared light provide support for symptoms including sleep and mood issues, cognitive changes, hair loss, gut and vaginal dysbiosis, skin problems, and vaginal tissue changes, while blue light may provide antimicrobial activity for menopausal acne and vaginal infections. Many different light therapy products are available - including panels, wraps, face masks, and pelvic wands – that provide light therapy support for different symptoms. Choose products that use LED lights to deliver red, infrared red, and blue light (where appropriate) at approximately the same intensity of the sun for best results.  For more information about Fringe light products, go to: https://fringeheals.com/shop-all-products/

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December 9, 2024

Red Light Therapy vs Ice

Red Light Therapy vs Ice. If you were to take a sample of doctors and athletic trainers and ask them what therapy they recommend that people use for post-exercise muscle recovery, you are guaranteed to find that a majority will tell you to apply ice.  Cryotherapy or icing has long been considered the gold standard for dealing with pretty much any kind of inflammatory process, including the muscle inflammation that occurs following strenuous exercise. Cryotherapy is a therapeutic technique that involves exposing the body or specific areas to extremely cold temperatures, typically using ice packs, cold water immersion, or specialized cryochambers. But research has now clearly shown that when you put icing head-to-head with Red Light Therapy – which uses red and/or near infrared light to influence biology - and look at which one works better to support exercise recovery, Red Light Therapy consistently comes out on top. In 2019, a scientific article was published that reviewed three clinical trials and two animal studies comparing cryotherapy to Red Light Therapy. Each human clinical trial administered both red and near infrared light, while the two animal studies used near infrared light only, and light or cryotherapy were applied following exercise. The outcome for each study was post-exercise muscle recovery. All five studies found that Red Light Therapy was superior to cryotherapy at improving outcomes related to exercise recovery. This included decreased delayed onset muscle soreness and reduced muscle inflammation. The research also showed that in contrast to Red Light Therapy, cryotherapy did nothing to prevent muscle damage from occurring following strenuous exercise, since markers of muscle damage like creatine kinase were only reduced with Red Light Therapy.  The superiority of Red Light Therapy over cryotherapy makes perfect sense when you consider the mechanisms of how the two modalities work. In a nutshell, red light therapy stimulates mitochondria to produce energy and modulate oxidative stress, decreasing cellular markers of inflammation. Red Light Therapy also induces cellular changes like increasing the production of growth factors. This is how it can have effects such as decreasing inflammation and healing damaged muscle fibers, and how it can positively influence many aspects of exercise recovery. In contrast, cryotherapy constricts blood vessels and decreases blood flow, which leads to less edema formation (swelling). This might reduce inflammation and decrease pain, but it really does nothing on a cellular level to support healing. In fact, it’s been argued by some experts to do the opposite. Several criticisms of cryotherapy have been raised, including that it only provides temporary relief and does not promote long-term healing. The studies described in this analysis used light that was quite low in intensity. Light intensity refers to the amount of light being delivered by a device. It is also sometimes called irradiance, and it’s usually measured in units called mW/cm2. Red Light Therapy devices on the market vary widely in terms of their intensity. While it’s common to see marketing claims that high intensity products (at upwards of 100mw/cm2) are needed to reap the benefits of Red Light Therapy, this research (and a lot of other studies too), show that this is false.  When it comes to using Red Light Therapy for post-exercise muscle recovery, research has clearly shown that more is not better. Instead of high intensity products, it’s best to use a device that delivers both red and near infrared light at a low to moderate intensity. Fringe Red Light Therapy products are great options for post-exercise support, delivering the optimal intensity of light at between 20 and 40mw/cm2. This is like the intensity of the sun. Fringe Red Light Therapy wraps even have the advantage of being portable and cordless, offering the flexibility of immediate use, including on the sideline! So, the next time you have a hard workout, reach for a Red Light Therapy device instead of ice to support muscle healing. And the advantages of Red Light Therapy over cryotherapy extend to healing for other conditions as well. Basically, you can use Red Light Therapy for anything that you would consider using ice for. By using Red Light Therapy instead, you’ll not only decrease pain and inflammation, but you’ll also activate cellular healing mechanisms that will help you to feel better faster. For more information about Fringe light products, go to: https://fringeheals.com/shop-all-products/

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August 23, 2024

Light Therapy and Vibration for Female Pelvic Health

One of our missions at Fringe is to create high quality, evidence-based light therapy products, and to make them readily accessible to consumers. Our goal is to help people heal from the conditions that commonly ail them – like arthritis, post-exercise muscle soreness, and eczema (just to name a few) - in the comfort of their own homes.  Recently, we turned our attention to some of the more common conditions affecting women and those born female at birth specifically: disorders of the female pelvis. Disorders related to female pelvic health (including pelvic floor pain and dysfunction, urinary incontinence, sexual dysfunction, and vaginal infections) are incredibly common, affecting up to 50% of the population at some point in their lives. shop fringe pelvic wand                                         Enter, the fringe pelvic wand In response, we made the Fringe Pelvic Wand - which combines light therapy with vibration, two well-established healing modalities - which may support recovery from these challenging issues.   What is red light? Light therapy (also known as photobiomodulation) is the application of light with specific wavelengths to the body for the purposes of influencing biology. The most common form of light therapy uses red light, which is visible as the color red, and/or near infrared light, which is not visible but can be felt as heat. Blue light is also used in many light therapy products, mainly for its antimicrobial effects. Red, near infrared, and blue light are naturally produced by the sun, which gives off solar radiation. The term radiation describes energy that is transmitted in the form of waves or particles. The spectrum of light in our environment consists of both light we can see (visible light) and light that our eyes can’t perceive (invisible light). This is called the electromagnetic spectrum. The visible light spectrum is quite narrow, consisting of wavelengths that range from 400 to 700nm and span from violet to red in color. Blue and red light are part of this visible light spectrum, while near infrared light is not. Different colors of light have different depths of skin penetration, with red and near infrared light penetrating the deepest.  While early research on light therapy used primarily lasers, more recent research has found that LED’s can also be used, which also have the advantage of applying light to a larger area of the body as well as an improved safety profile. The use of LED in red/near infrared/blue light therapy devices has also greatly reduced the cost of treatment, making it something that can be done in the comfort of one’s own home. Both laser and LED lights have been used in research and practice to support pelvic health. Light therapy delivers light at a measurable level of intensity, which can be generally classified as low, moderate, and high. The intensity of sunlight is between 20 and 40mW/cm2, which is described as the “sweet spot” between higher intensities, which can have harmful effects, and lower intensities, which will have no effect at all. This range is optimal for healing while minimizing adverse effects, and is the range used in the Fringe Pelvic Wand. How might light therapy support female pelvic health? Light therapy may have physiological effects related to female pelvic health, including:                                                       Tissue Rejuvenation Loss of connective tissue, such as collagen and elastin, in the female pelvis is commonly experienced by women as they age and can also occur because of childbirth and infections. Through its effects on mitochondria, light therapy (especially red and near infrared light) may increase cellular energy production and increase connective tissue production. Light therapy may also modulate the production of reactive oxygen species, causing a shift towards tissue rejuvenation rather than breakdown, and may support muscle strengthening.                                                                                                         Reduced Inflammation & Pain Chronic pain is commonly associated with disorders of the pelvic floor, which may also be associated with pelvic inflammation. Light therapy (especially with red and near infrared light) may have powerful effects on inflammation. Studies have found that light therapy may affect levels of many molecules involved in inflammation, including reactive oxygen species, reactive nitrogen species, and prostaglandins.        Increased Blood Flow A decrease in blood flow to tissues in the female pelvis, especially the vagina, occur with age. This loss of blood flow negatively affects tissues by reducing the supply of oxygen and nutrients and contributes to age associated changes such as vaginal atrophy. Light therapy (especially red and near infrared light) may increase blood flow in two ways. First, it may increase levels of nitric oxide through its effects on the mitochondria, which causes vasodilation. The dilation of blood vessels allows more blood to flow through. Second, it may increase angiogenesis, which is the synthesis of new blood vessels. A greater density of blood vessels may increase the delivery of blood to tissues.       Effects on Microorganisms Infections with pathogenic microorganisms in the female pelvis are quite common, and include bacteria (such as chlamydia), fungi (such as candida), and viruses (such as HPV). The vagina also naturally hosts the vaginal microbiome, which has a balance of microorganisms. When imbalanced, susceptibility to infections and bacterial vaginosis is increased. Light may have effects on microorganisms, both pathogenic and non-pathogenic. Blue light may have powerful effects on pathogenic microbes that can infect the vagina, such as candida, while red light may have positive effects on the microbes that comprise the microbiome, including the vaginal microbiome.                                                         Some clinical conditions related to female pelvic health that may improve with light therapy include: Vaginal candidiasis Human papillomavirus and associated vaginitis and cervicitis Vulvovaginitis Chronic pelvic pain Urinary incontinence and sexual dysfunction Overactive bladder Interstitial cystitis/bladder pain syndrome Menopause Episiotomy recovery   What is vibration therapy? Vibration therapy may have physiological effects related to female pelvic health, including: Tissue Rejuvenation Vibration therapy may have many effects on cells associated with the structural integrity of the female pelvic. Collagen in particular may respond to vibration therapy, especially at low magnitudes, and both collagen and muscle formation respond well to low magnitude vibration at between 8 and 10Hz. Increased Blood Flow Vibration therapy may increase blood flow, after as little as 10 minutes of therapy. Increasing blood flow helps to perfuse tissues with oxygen and nutrients and improve function and speed healing.  Muscle Tone Regulation While proper functioning of the pelvic floor muscles is integral to bowel, bladder, and sexual health, in many women these muscles are weak. Others experience chronic hypertonicity in muscles of the pelvic floor, which is also suboptimal. Vibration therapy may regulate muscle tone in two ways. First, it may decrease spasticity in muscles that are overactive. Second, it may improve the potential to voluntarily contract muscles, such as those of the pelvic floor, which are poorly controlled in between 30 and 50% of women, and in this way activate and strengthen the muscle. Muscle tone regulation is accomplished by activating muscles via a spinal reflex and increasing blood flow. Decreased Pain Vibration therapy may reduce many different pain types, including neuropathic pain, low back pain, and muscle pain. This may happen via several mechanisms, such as regulating muscle tone and increasing blood flow. Some clinical conditions related to female pelvic health that may improve with vibration therapy include Urinary incontinence Pelvic floor dysfunction Vulvodynia (a pelvic pain condition) Pelvic pain penetration disorder Sexual dysfunction The Fringe Pelvic Wand The Fringe Pelvic Wand delivers three wavelengths of light via three modes:    + Mode 1 - Deep Rejuvenation MODE ONE - red/near infrared light (630nm & 830nm): delivers both red (630nm) and near infrared (830nm) light to the pelvic tissues. This mode may help with pelvic pain and inflammation; bladder and muscle health; optimizing the vaginal microbiome; increasing the production of collagen and elastin; and improving blood flow and tissue health. Use Mode 1 for deep pelvic rejuvenation if you are NOT sensitive to light or heat. + Mode 2 - Antimicrobial MODE TWO - Blue Light (415 nm): delivers blue light (465nm) to the pelvic tissues. This mode may support the destruction of microbes including fungus and bacteria and healing from yeast infections and bacterial vaginosis. + Mode 3 - Rejuvenation MODE THREE - Red Light (630 nm): delivers only red (630nm) light to the pelvic tissues. This mode may help with pelvic pain and inflammation; bladder and muscle health; optimizing the vaginal microbiome; increasing the production of collagen and elastin; and improving blood flow and tissue health. Use Mode 3 for pelvic rejuvenation if you ARE sensitive to light or heat.     The Fringe Pelvic Wand also delivers optional vibration, via four modes:   + Mode 1 - 10hz (default mode) MODE ONE: provides very low frequency vibration which may help to support muscle relaxation and pain reduction. + Mode 2 - 50hz MODE TWO: provides low/moderate frequency vibration which may help to support muscle relaxation, reduce pain, and increase awareness of pelvic muscle function. Mode 2 can be combined with gentle pelvic floor exercises. + Mode 3 - 90hz MODE THREE: Provides moderate/high frequency vibration that increases awareness of pelvic muscle function and may help to support pelvic muscle contraction. Mode 3 can be combined with moderately active pelvic floor exercises. + Mode 4 - 120hz MODE FOUR: provides high frequency vibration that may help to support strengthening of pelvic muscles. Mode 4 can be combined with active pelvic floor exercises.       Let's get started How to use the fringe pelvic wand Light & Vibration Therapy Safety The safety of light and vibration therapy has been demonstrated in thousands of research studies. However, there are some precautions to be aware of before you begin your therapeutic journey.Photosensitivity is the main contraindication to light therapy. If you are sensitive to light or are using medications that increase light sensitivity (see https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672668/ for a recent list), you may need to reduce treatment time, interval, and/or frequency, as well as reduce light intensity. Light & Vibration Therapy Safety Here are some other precautions to consider. Please don’t: Exceed the recommended treatment times and frequency. Use on open fresh wounds. Use in combination with lotions, balms or other topical products that contain heat producing ingredients. Use with a non-water based lubricant. If you’re pregnant, we recommend checking with your health care provider to see if they think it’s appropriate for you to use the Fringe Pelvic Health Wand. They can assess your unique health needs and determine if light and vibration therapy is right for you. However, we do know that it’s a great tool to use postpartum when it may help to support healing and recovery of pelvic tissues. Co-Author Elizabeth Frey, FCAMPT, MCISC (MANIP), MSc. PT, MSc, BPHE, BSc, MCPA - Fringe Pelvic Health Advisor Liz holds a BSc and BPHE from Queen’s University; a MSc in Exercise Physiology from the University of Toronto, a MSc (PT) from McMaster University, and a MCISC (Manip) from University of Western Ontario. Liz is a clinic owner and practicing physiotherapist with a specialty in pelvic health physiotherapy. She is a clinical lab facilitator at the University of Toronto, and a clinical supervisor for physiotherapy students. As an orthopaedic and pelvic health physiotherapist, Liz integrates her over 10 years of clinical expertise to provide a unique whole-body approach to wellness. Liz’s practice focuses on helping women navigate pregnancy, menopause, and everything in between. The contents in this blog; such as text, content, graphics are intended for educational purposes only. The Content is not intended to substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your healthcare provider.  

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March 15, 2024

Light Therapy for Brain Health

Light Therapy for Brain Disorders Our understanding of brain health as being fundamental to our overall well-being dates to the time of the ancient Greeks. “Mens sana in corpore sano”, which translates to “a healthy mind in a healthy body”,  was a foundational part of the Hippocratic philosophy. Hippocrates introduced the first classification of mental disorders and believed that the brain was the organ responsible for mental illnesses. His classes of mental disorders included melancholia, mania, insanity, and others. While those terms are no longer in use today, many modern brain disorder, such as depression and dementia, are foundationally like those ancient classifications. Importantly, Hippocrates believed that “natural” treatments would cure diseases. One such therapy was the use of sunshine, known as “heliotherapy”. shop red light therapy head wrap   Brain disorders In modern society, brain disorders are becoming increasingly prevalent. Also referred to as neurological disorders, these conditions are estimated to be the second leading cause of death, causing 9 million deaths globally each year. While these diseases yield a massive economic burden in terms of health care costs, they also have an enormous impact on our quality of life. The prevalence of brain disorders is expected to increase significantly over the next several decades as the population both ages and grows.      Categories of brain disorders There are several different categories of brain disorders. These include: autoimmune diseases (such as multiple sclerosis – MS), epilepsy, psychiatric disorders (such as depression and anxiety), neurodegenerative diseases (such as Alzheimer’s and Parkinson’s disease), neurodevelopmental disorders (such as ADHD and autism), stroke, traumatic brain injuries (such as concussions and chronic traumatic encephalitis), and brain tumors.     While these disorders are all unique, they share fundamental pathological characteristics. Most involve an increase in oxidative stress, which involves excessive production of reactive oxygen species. The brain is especially vulnerable to oxidative stress because it has a high metabolic rate, and oxidative stress can occur both in chronic diseases (such as Alzheimer’s) and acute conditions (such as concussions). Alterations in brain metabolism are also common, which can precede and co-occur with oxidative stress. Brain metabolism accounts for around 20% of total metabolism, even though it only contributes 2% of total body weight. This makes the brain vulnerable to damage from metabolic effects such as those that occur with aging, poor diet, and trauma.  Neuroinflammation, which involves inflammation in the brain as a response to disease and injury, also occurs. Oxidative stress, impaired metabolism, and neuroinflammation overlap, involving many of the same molecules.  Brain disorders are notoriously difficult to treat. Because the blood brain barrier restricts entry of foreign substances into the brain, drug transport into the brain is limited. We are also limited by our lack of understanding these diseases. Experts admit that we actually know very little about how the brain works, for a variety of reasons. Given this complexity, using non-pharmacological interventions to treat the foundational pathologies of brain diseases (including oxidative stress, impaired metabolism, and neuroinflammation) is a great starting point. Light therapy, or photobiomodulation, is one such approach.               Light therapy Light therapy (also known as photobiomodulation) is the application of light with specific wavelengths to the body for the purposes of influencing biology. The most common form of light therapy uses red light (RL), which is visible as the color red, and/or near infrared light (NIRL), which is not visible but can be felt as heat. The RL used in light therapy usually ranges from 600 to 700 nanometres (nm), with the unit nm referring to distance the light wave travels in one cycle. The NIRL used in light therapy usually ranges from 800 to 900nm.   RL and NIRL are naturally produced by the sun, which gives off solar radiation. The term radiation describes energy that is transmitted in the form of waves or particles. The spectrum of light in our environment consists of both light we can see (visible light) and light that our eyes can’t perceive (invisible light). This is called the electromagnetic spectrum. The visible light spectrum is quite narrow, consisting of wavelengths that range from 400 to 700nm and span from violet to red in color. RL is part of this visible light spectrum, while NIRL is not. Red and near infrared light therapy is the application of artificially generated light in the red and near infrared spectral bands. The term “red light therapy” usually describes the use of both RL and NIRL, although only the red light produced by the device is visible to the naked eye. IRL can still be perceived by the body as heat when it contacts skin. How Does Red Light Therapy Affect Brain Health? Light therapy, specifically the application of red and near infrared light, positively impacts all three foundational pathologies of brain disorders: oxidative stress, impaired metabolism, and neuroinflammation. Oxidative Stress: Light is absorbed in cells by molecules called chromophores, many of which are found inside the mitochondria. Mitochondria are involved in regulating the production the reactive oxygen species that cause oxidative stress when present in high amounts. Light therapy has been shown to modulate oxidative stress and reactive oxygen species production. Impaired Metabolism: Through its impact on mitochondria, light also affects metabolism. In addition to regulating reactive oxygen species production, mitochondria also make the energy currency of the cell, called ATP. Specifically, RL and NIRL stimulates cytochrome c oxidase, a mitochondrial enzyme that produces ATP. This increases ATP synthesis which provides more energy to brain cells. Neuroinflammation: Red and NIRL have anti-inflammatory effects, and unlike anti-inflammatory medications (such as NSAID’s), do not cause side effects. Studies have found that light therapy affects levels of many molecules involved in inflammation, including reactive oxygen species, reactive nitrogen species, and prostaglandins. Red and NIRL therapy have specifically shown to reduce neuroinflammation.  Brain Disorders Treated by Red Light Therapy Since RL and NIRL therapy (hereafter referred to simply as “light therapy”) can positively impact the foundational pathology that characterizes so many brain disorders, it is not surprising that there is evidence to support its use in conditions ranging from Alzheimer’s Disease to traumatic brain injury. Here are the top 10 brain disorders that may benefit from RL and NIRL therapy, as supported by scientific research.    Alzheimer’s Disease & Dementia Alzheimer’s Disease (AD), a form of dementia, is a neurodegenerative disease that comprises 70% of dementia cases. AD affects 1 in 10 US adults over the age of 65, or 5.7 million Americans. AD is a progressive disease that is characterized by memory loss, disorientation, behavior changes, and an eventual loss of independent functioning. Research investigating the use of light therapy for AD is extensive, with dozens of studies published in the last decade. While many studies have used light therapy in animal models of AD, several clinical trials have been published which have shown positive results. Most studies have exclusively used NIRL, which has been found to penetrate more deeply into the brain.    A few studies have used unique research approaches to treating AD with light therapy. For example, a 2022 clinical trial combined light therapy to the brain with RL and NIRL therapy to the gut in patients with mild to moderate AD. The control group received sham, or placebo, light therapy. Patients receiving RL and NIRL showed improved cognitive function relative to the control group. The gut microbiome has been proven to play a role in maintaining brain health, and responds positively to light therapy. Another study combined light therapy with exercise in patients with AD. Patients in both the treatment and control groups participated in a moderate intensity exercise program 3 days per week, 45-60 minutes per session, for 3 months. Patients in the treatment group received NIRL through the nose and on wrist acupuncture points, while those in the control group received a sham light treatment. Both groups improved, but the group receiving NIRL showed more positive change.  Researchers state that there are many benefits of light therapy in AD that occur on a cellular level. These include improving mitochondrial function and increasing ATP production, decreasing neuroinflammation, and decreasing oxidative stress – which have a downstream effect of decreasing brain amyloid plaque accumulation.   While AD is the most common form of dementia, there is also non-Alzheimer’s dementia, which is similarly characterized by memory loss, disorientation, behavior changes, and an eventual loss of independent functioning. Although most research studies distinguish between types of dementia, some do not, and group all forms of dementia together. It’s not clear how important this distinction is, since the disorders share the same foundational pathologies, so light therapy is likely to have a similar impact regardless of the categorization of dementia. However, it’s still worth looking at some of this evidence. Mild cognitive impairment (MCI), which often progress to dementia, is also included here. A 2021 comprehensive review of dementia of all types assessed 10 studies of dementia patients treated with light therapy (either RL or NIRL). While not all studies were considered high quality, every one of them reported positive results. Included here was a study of a patient with mild dementia, as well as one of MCI. This analysis suggests that light therapy can benefit dementia starting from very early stages.  Another mechanism of how light therapy affects the brain of patients with dementia was revealed in a 2021 trial. In this study, cerebral blood flow was analyzed along with cognition. In addition to improvements in cognitive function, patients also had more blood flow in several areas of the brain. The authors suggest this may be due to changes in levels of nitric oxide.       Cognition In addition to improving brain health in people suffering from impaired cognitive function (such as AD, non-Alzheimer’s dementia, and MCI), light therapy has also been found to improve cognition in healthy people. This is quite remarkable, as it shows that the benefits of light therapy are quite universal.     Researchers have shown in a series of controlled clinical studies that light therapy using NIRL improves cognition in young and middle-aged healthy adults when applied to the prefrontal cortex of the brain. Cognitive improvements were accompanied by changes in brain function using tools such as EEG, fMRI, and brain blood flow.  In 2019, a meta-analysis of all the research looking at the effects of light therapy (including either NIRL or NIRL/RL combined) on cognition in healthy subjects was published. Seven studies included subjects aged 17 to 35 while two studies included subjects aged 49 and older. Despite some issues with study quality, the overall effect on cognition was found to be positive, leading the authors to conclude that light therapy is a “cognitive-enhancing intervention in healthy individuals”.       Parkinson's Disease Parkinson’s disease (PD) is a degenerative brain disease that involves damage to dopamine producing neurons in the brain. PD involves motor symptoms (such as balance and gait problems) and non-motor symptoms (such as depression, sleep disorders, and cognitive impairment). PD affects around one million people in the US, and over 10 million people globally.      Studies using light therapy to treat PD patients have shown that it is helpful. For example, one study of patients who used at-home NIRL therapy devices showed improvements in balance, fine motor skills, cognition, and mobility after 12 weeks of treatment. Patients applied the light to the head, neck, and abdomen. Research suggests that in PD, light therapy should be used 2-3 times per week for at least four weeks.  Animal models of PD have been used to try to determine precisely how light therapy is working. A 2020 analysis of 28 animal studies concluded that light therapy, including both RL and NIRL, is “an effective method to treat animal models of PD”. It is suggested that these benefits are due to effects on mitochondria, oxidative stress, and brain metabolism, which may be “helping the brain to repair itself”. The effects of light therapy on mitochondria may be especially important in PD, which involves significant mitochondrial dysfunction.        Stroke Stroke (Ischemic) – Ischemic stroke is a type of cardiovascular disease in which the blood flow to the brain is disrupted. Annually, close to 800 000 people have strokes in the US, with an economic cost of close to 57 billion dollars. Although some people recover fully from a stroke, it can cause permanent disability and death. The risk of stroke increases with age, but it can occur across all age groups.        Light therapy has shown small, but promising, effects in studies with stroke patients. Using NIRL laser light technology, it was found that treatment improved outcomes when used within 24 hours after a stroke. A larger follow up study showed smaller effects, but there was still a positive trend towards better outcomes.  Studies of animal models have shown many benefits when light therapy is used shortly after a stroke occurs. These include increasing the production of new neurons (neurogenesis), decreased inflammation, and improved mitochondrial function. The effects of light on mitochondria is very important in improving stroke outcomes, since mitochondria are responsible for protecting and maintain neurons. Light therapy may work synergistically with other non-invasive treatments for stroke, such as Coenzyme Q10.        Depression Depression – Depression is a highly prevalent mood disorder, affecting at least 21 million people in the US in 2021. Depression disproportionately affects young people, with considerably higher rates in people aged 18-25. While depression is associated with psychosocial factors such as trauma, there is also often an underlying brain pathology. In particular, depression has been associated with impaired functioning of brain mitochondria, neuroinflammation, and oxidative stress. Impaired mitochondrial functioning in depression is not just limited to the brain, but rather is found throughout the body and corresponds with symptom severity.   Given these associations, it is not surprising that light therapy can be used to treat depression. Several clinical trials of light therapy in depression have been conducted, all of which used NIRL applied directly to the head. A 2022 systematic review concluded that NIRL therapy “can be classified as strongly recommended for moderate grade of major depressive disorder”. Similarly, a 2023 meta-analysis concluded that there is a “promising role of in the treatment of depressive symptoms”. Multiple Sclerosis Multiple sclerosis (MS) is an autoimmune neurodegenerative disease that involves the brain and spinal cord. The prevalence of MS has recently been found to be higher than originally thought, affecting nearly 1 million people in the US. The symptoms of MS vary between affected individuals, and include fatigue, gait problems, numbness/tingling, weakness, spasticity, and vision problems. Interestingly, MS prevalence shows a north south gradient, in which people at northern latitudes have more disease. Low sun exposure is a known risk factor for MS, while greater exposure is associated with decreased disease severity. MS involves considerable neuroinflammation, as well as increased oxidative stress.     Since most research related to sun exposure and MS has focused on vitamin D – which is produced from UV light, rather than RL or NIRL – there are only a few studies looking at how RL and NIRL therapy (which does not stimulate vitamin D production) affects MS. However, the research that has been done has been very positive. Notably, only one study (using a mouse model of MS) applied light therapy to the brain, with mice showing improved motor function and decreased brain pathology following treatment. Other animal studies have applied light to the spinal cord, which was also the target of a study with human MS patients. A second study of human MS patients applied light to the inside of the mouth and the radial artery on the wrist. Since MS affects both the brain and the peripheral nervous system, it appears that light therapy can target the multiple areas and still be beneficial.     Autism Spectrum Disorder Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that manifests in childhood. ASD is characterized by difficulties with social interactions, abnormal language, and restricted/repetitive behaviors, interests, and activities. ASD is a term that includes a range of disorders, including both genetic and non-genetic conditions. Some people with ASD are high functioning, while others suffer from serious disability. ASD is highly prevalent, affecting 1 in 36 children in 2020.     Two studies have investigated whether light therapy can be used to improve symptoms of autism. In the first, adults with high functioning ASD received transcranial PBM for 8 weeks. Treatment caused a significant improvement in social responsiveness scores, social awareness, social communication, social motivation, and restricted/repetitive behaviors. In the second, Transcranial PBM with a RL & NIRL laser was used for the treatment of irritability associated with autistic spectrum disorder in children and adolescents aged 5-17 years. Light therapy significantly reduced irritability scores compared to the placebo group, as well as lethargy and social withdrawal, stereotypic behaviour, hyperactivity and non-compliance, and inappropriate speech. Benefits were maintained at both 6 and 12 month follow up. The long-lasting benefits seen in this study are striking, and suggest that brain structure and/or function has improved as a result of treatment with RL and NIRL.       Epilepsy Epilepsy is a brain disorder that causes seizures, which are discharges of electrical activity in the brain. Epilepsy affects 1.2% of the US population, or approximately 3.4 million people. Epilepsy is most commonly treated with drugs, but up to 1/3 of people do not improve with medication. Surgery is another treatment for epilepsy, but it carries some risk.      Although research on light therapy and epilepsy has so far been limited to animal models, the impact of light on seizures and brain health has been positive. A 2022 review article described that “ makes the neurons ‘healthier’ by restoring their function and making them more resistant to distress and disease”. Several animal studies using NIRL have observed positive outcomes, including reduced seizure activity and decreased mortality. This is consistent with research that shows a north south disease gradient with epilepsy, similar to that observed with MS.      Traumatic brain injury / concussion Traumatic brain injuries (TBI) occur when there is a violent blow to the head. Concussions are a common type of TBI. Symptoms include nausea, vomiting, vison and speech problems, and difficulty with memory and concentration. Around 1.7 million people in the US experience a TBI annually, with adolescents aged 15 to 19 and older adults over 65 years being affected more commonly.     Research using light therapy (both RL and NIRL) for TBI has looked at both immediate and chronic effects in animal and human models. Animal studies have shown a reduction in the size of the brain lesion when light therapy was used immediately following trauma, which correlated with the severity of neurological symptoms. Similarly, a case study of a hockey player with a history of six documented concussions using at-home intracranial and intranasal NIRL found improved markers of health using brain imaging. Other human studies looking at behavioral outcomes have observed benefits such as improved sleep, improved cognition, and reduced anxiety and depression.        Chronic Traumatic Encephalitis Chronic traumatic encephalitis (CTE) is a brain disorder caused by repeated head injuries. The injuries damage brain neurons and the condition worsens over time. CTE occurs most commonly in athletes that play contact sports, like football and boxing. CTE highlights the importance of healing traumatic brain injuries, as approximately 17% of people with repeated TBI progress to CTE.     As with TBI, light therapy has been found to benefit CTE. A study of four ex-football players with suspected CTE treated with RL and NIRL to the head found that three of the four players showed improvements in outcomes including depression, pain and sleep. More research is needed to confirm these preliminary findings.   Using Light Therapy for Brain Health There are an increasing number of devices on the market that directly target brain health. Most apply light therapy to the head (often as a hat or helmet), some deliver light to the brain through the nose (intranasally), some target specific areas only (such as the forehead or back of head), and some even shine light on distant areas on the body (such as the abdomen). With so many options available, how can you know which device is best for you? Here are five issues to consider. Style Preference: Your personal level of comfort with a device is important. If it isn’t easy to use, and if it doesn’t feel good on your body, you probably won’t use it consistently. Imagine yourself wearing the device – would you be comfortable wearing a hard helmet, or would you prefer a soft hat? Do you want a device that is wireless, or can you commit to being close to an electrical outlet so that you can plug it in? Do you want the flexibility of being able to lie down while wearing the device? Are you comfortable with having multiple contact points on the body, or would you prefer the device be on only one part? Think about your personal preferences and choose accordingly. Laser vs LED: Light therapy is administered using either laser or LED lights. While early light therapy research was done using lasers, LED lights have become much more popular over the last decade. The research described in this article includes both types of light sources. In 2018, Dr. Michael Hamblin – the world’s leading light therapy expert – concluded that LED lights using comparable parameters to lasers performed “equally well”, which is very important because LED powered light therapy devices can be made at a fraction of the cost of laser devices. Consumers can rest assured that using at home LED powered devices for the treatment of brain disorders is supported by research evidence. For at home use, look for a device that uses LED lights as safe and affordable option. Light Color/Wavelength: As described in this article, both RL and NIRL have been used in studies of light therapy to treat brain disorders. Although NIRL has been used most often, some studies have also found benefit from RL. Light with wavelengths between 600 and 1300nm, in the red and near infrared light spectrums, have been found to penetrate maximally into the brain. So, look for products that provide both RL and NIRL in combination, or NIRL only. Light Intensity: Light intensity refers to the amount of light being delivered by a device. It is also referred to as irradiance. The required intensity when using light therapy to impact brain disorders is unclear. The assumption is often made that for light to influence the brain, it must receive light photons, which must pass through the hair, skin, skull, and cerebrospinal fluid. Studies have found that the deepest penetration comes from higher intensity light sources using NIRL. However, studies have also shown that there are benefits to light therapy that can’t be explained by the depth of light penetration into the brain. For example, cognition and blood flow in the brain have been found to improve when light therapy is applied to the front and back of the neck. Similarly, depressive symptoms improve when light therapy is applied to either the periphery of the body, as well as directly to the brain. Although this isn’t well understand, there are several possible explanations, including effects on superficial blood and lymphatic vessels in the head and neck area as well as connections between the brain and other areas of the body, such as the gut. These “indirect” benefits to the brain from applying light therapy to somewhere on the body are increasingly being recognized as being neuroprotective. The penetration issue has led many companies to develop high intensity devices to support brain health. While these devices have been found to helpful, devices that are lower intensity have been also. Devices across a range of intensities may provide benefit, and consumers aren’t limited to a specific intensity range. Education: While light therapy education will not change the specific functionality of a device, it does have the potential to profoundly impact how someone uses the technology. When a company provides evidence-based education that teaches consumers why, how, and when to use a product, devices can be used to better support healing. Look for products with accompanying education and instructions for use, whether in printed and/or digital formats. You can also look for companies that provide support by phone or email to current or prospective customers.   Conclusion Light therapy with red and near infrared light has shown great promise in supporting brain health. Benefits of treatment have been observed across a wide range of populations, ranging from young healthy adults to elderly people with dementia. Light therapy affects the foundational pathologies that underlie virtually all brain disorders, including oxidative stress, impaired metabolism, and neuroinflammation. This occurs, at least in part, through stimulation of brain mitochondria, which produce energy.  Research using light therapy to support brain health has applied a range of technical specifications, including style of device, light source, light wavelength, and light intensity. Benefits have been observed in most studies, which suggests that consumers have options when it comes to choosing the device that is right for them. Factors such as comfort, cost, and ease of use can be considered. Therapy with RL and NIRL can be used to safely support brain health across the lifespan, making light therapy devices a wise investment for all.     shop red light therapy head wrap   For more information about Fringe light products, go to: https://fringeheals.com/shop-all-products/

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